Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly
Identifieur interne : 000263 ( Main/Exploration ); précédent : 000262; suivant : 000264Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly
Auteurs : Hirohisa Masuda [Royaume-Uni] ; Risa Mori [Royaume-Uni] ; Masashi Yukawa [Royaume-Uni, Japon] ; Takashi Toda [Royaume-Uni]Source :
- Molecular Biology of the Cell [ 1059-1524 ] ; 2013.
Abstract
A microtubule nucleator γ-tubulin forms a multiprotein complex (γ-tubulin complex or γ-TuC), which localizes to the microtubule organizing centers (MTOCs). We identify fission yeast Mzt1/MOZART1 as a novel conserved stoichiometric component of the γ-TuC. Mzt1 is required for cell viability, microtubule organization, and γ-TuC localization to the MTOCs, yet the core γ-TuC assembles in its absence.
Url:
DOI: 10.1091/mbc.E13-05-0235
PubMed: 23885124
PubMed Central: 3771951
Affiliations:
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type="wicri:Area/Main/Exploration">000263</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly</title><author><name sortKey="Masuda, Hirohisa" sort="Masuda, Hirohisa" uniqKey="Masuda H" first="Hirohisa" last="Masuda">Hirohisa Masuda</name><affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Mori, Risa" sort="Mori, Risa" uniqKey="Mori R" first="Risa" last="Mori">Risa Mori</name><affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Yukawa, Masashi" sort="Yukawa, Masashi" uniqKey="Yukawa M" first="Masashi" last="Yukawa">Masashi Yukawa</name><affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima 739-8530, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima 739-8530</wicri:regionArea><wicri:noRegion>Higashi-Hiroshima 739-8530</wicri:noRegion></affiliation></author><author><name sortKey="Toda, Takashi" sort="Toda, Takashi" uniqKey="Toda T" first="Takashi" last="Toda">Takashi Toda</name><affiliation wicri:level="1"><nlm:aff id="aff1">Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author></analytic><series><title level="j">Molecular Biology of the Cell</title><idno type="ISSN">1059-1524</idno><idno type="e-ISSN">1939-4586</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>A microtubule nucleator γ-tubulin forms a multiprotein complex (γ-tubulin complex or γ-TuC), which localizes to the microtubule organizing centers (MTOCs). We identify fission yeast Mzt1/MOZART1 as a novel conserved stoichiometric component of the γ-TuC. 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sortKey="Doxsey, Sj" uniqKey="Doxsey S">SJ Doxsey</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Japon</li><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Masuda, Hirohisa" sort="Masuda, Hirohisa" uniqKey="Masuda H" first="Hirohisa" last="Masuda">Hirohisa Masuda</name></noRegion><name sortKey="Mori, Risa" sort="Mori, Risa" uniqKey="Mori R" first="Risa" last="Mori">Risa Mori</name><name sortKey="Toda, Takashi" sort="Toda, Takashi" uniqKey="Toda T" first="Takashi" last="Toda">Takashi Toda</name><name sortKey="Yukawa, Masashi" sort="Yukawa, Masashi" uniqKey="Yukawa M" first="Masashi" last="Yukawa">Masashi Yukawa</name></country><country name="Japon"><noRegion><name sortKey="Yukawa, Masashi" sort="Yukawa, Masashi" uniqKey="Yukawa M" first="Masashi" last="Yukawa">Masashi Yukawa</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|wiki= Wicri/Musique
|area= MozartV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3771951
|texte= Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23885124" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MozartV1
| This area was generated with Dilib version V0.6.20. |  |